Table 1. Clinical description of the cohort by study centre: University of British Columbia (UBC) and University of California San Francisco (UCSF).
| Number (%), and Median (25th-75th percentile) | UBC | UCSF | |
|---|---|---|---|
| N=23 | N=69 | ||
| Preoperative factors | |||
| Gestational age at birth (wk) | 39 (38-40) | 39 (38-40) | |
| Birth weight (g) | 3250 (2955-4015) | 3364 (3000-3609) | |
| Male | 13 (57%) | 46 (67%) | |
| Apgar score at 5 minutes | 8 (7-9) | 8 (8-9) | |
| Caesarean delivery | 5 (22%) | 19 (28%) | |
| Heart lesion | TGA | 21 (91%) | 41 (59%) |
| SVP | 2 (9%) | 28 (41%) | |
| Days mechanically ventilated | 5 (3-7) | 6 (4-9) | |
| Intra-operative factors | |||
| Operation type | Arterial Switch | 19 (83%) | 40 (58%) |
| Norwood | 2 (9%) | 25 (36%) | |
| Other | 2 (9%) | 4 (6%) | |
| Bypass type | None | 2 (9%) | 3 (4%) |
| Low flow | 1 (4%) | 5 (7%) | |
| Full flow | 18 (78%) | 44 (64%) | |
| Regional cerebral perfusion | - | 12 (17%) | |
| Deep hypothermic cardiac arrest | 2 (9%) | 2 (3%) | |
| Other | - | 3 (4%) | |
| Postoperative factors | |||
| ECLS | 4 (17%) | 7 (11%) | |
| MRI 1 | |||
| MRI day (at day's of life) | 5 (4-12) | 5 (3-6) | |
| Acquired injury | 12 (52%) | 28 (41%) | |
| WMI | 7 (30%) | 14 (20%) | |
| IVH | 3 (13%) | 4 (6%) | |
| Stroke | 8 (35%) | 15 (22%) | |
| MRI 2 | |||
| MRI day (at day's of life) | 21 (17-29) | 20 (16-25) | |
| Acquired injury | 8 (47%) | 24 (40%) | |
| New WMI | 5 (29%) | 19 (32%) | |
| New IVH | - | 1 (2%) | |
| New stroke | 3 (18%) | 5 (8%) | |