Skip to main content
. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: J Mol Cell Cardiol. 2010 May 13;49(3):362–369. doi: 10.1016/j.yjmcc.2010.05.001

Figure 1. UTP induces proliferation and migration of rat cardiac fibroblasts.

Figure 1

(A) Proliferation of passage 1 rat CFs serum-starved for 24h and stimulated with 10 µM UTP was examined by [3H]thymidine incorporation. UTP increased [3H]thymidine incorporation by 30% after 24 h. (B) Fibroblast migration was assessed by a modified Boyden chamber method in the absence (control) or presence of 10 µM UTP for 24 h. The data are shown as the fold-increase relative to control and are mean ± SEM of at least 3 independent experiments performed in triplicate and compared by using Student’s t test. *, p < 0.05 and ***, p < 0.001 in response to UTP.