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. Author manuscript; available in PMC: 2011 Sep 1.
Published in final edited form as: Neurosci Res. 2010 Jun 8;68(1):1–8. doi: 10.1016/j.neures.2010.06.001

Fig. 4. Effects of repeated AMPH administration on ASIC1 and ASIC2 expression in the NAc.

Fig. 4

(A and B) Repeated AMPH administration increased ASIC1 levels in surface (S) and intracellular (I) pools. (C) Repeated AMPH administration did not alter the S:I ratio of ASIC1. (D and E) Repeated AMPH administration had no effect on ASIC2 levels in surface and intracellular pools. (F) Repeated AMPH administration did not alter the S:I ratio of ASIC2. (G and H) Repeated AMPH administration had no effect on α-actinin expression. Rats were injected with saline or AMPH (once daily for 7 days; 1.25 mg/kg for the first and last injections and 4 mg/kg for the middle 5 daily injections). Animals were sacrificed at 14 days after the last injection. The NAc tissue was dissected for the surface cross-linking experiments with BS3. Data are expressed in terms of means ± SEM (n = 6 per group). *p < 0.05 versus saline.