Fig. 5. Cellular immune responses after challenge.
Cellular immune responses were determined in splenocyte cultures and lung suspensions. (a) IL-4 levels determined from 72-h splenocyte culture after isolation from immunized and unimmunized mice at four days after challenge and re-stimulation with HA Class I and II influenza peptides. (b) IFN-γ levels in 72-h splenocyte cultures. (c) Lung IL-21. (d) Lung IFN-γ. (e) Lung TNF-α. (f) Lung IL-12p70. Groups are as described in Fig. 3.