Table 3.
Mean±SEM of Diastolic and developed LV stiffness (n=6 per genotype)
Diastolic stiffness | Developed stiffness | |||
---|---|---|---|---|
Treatment | WT | KO | WT | KO |
Dobutamine | 2.9±0.3 | 6.1±0.7## | 7.0±0.4 | 10.1±1.2 # |
Propranolol | 3.2±0.3* | 6.1±0.7# | 4.0±0.4** | 5.9±0.6**/ # |
Stiffness: slope of wall stress (in mmHg) vs. LV volume (in µl) relation;
Asterisks: comparison between dobutamine and propranolol results using a paired t-test;
Number sign: comparison between WT and corresponding KO result using a t-test.