Figure 5. Relevant source of IL-1R and Psgl-1 for endothelial selectin regulation.
A) sP-sel levels in IL-1R+/+ mice that had received IL-1R−/− bone marrow (n=4) and IL-1R−/− mice that had received IL-1R+/+ bone marrow (n=6) before IL-1β injection (black bars) and 5 hours following IL-1β injection (white bars). B) sP-sel levels in Psgl-1−/− mice that had received Psgl-1+/+ marrow (n=3) and Psgl-1+/+ mice that had received Psgl-1−/− marrow (n=6) before IL-1β injection (black bars) and 5 hours following IL-1β injection (white bars). *p<0.05. ***p<0.001.