Table 2.
Adverse Event | Grade | 500mg | 2000mg |
---|---|---|---|
Lymph node pain | 3 | 1 | 0 |
Lymphatics-other | 3 | 1 | 0 |
↓ Neutrophil count | 3 | 0 | 1 |
Anorexia | 2 | 2 | 0 |
Arthritis | 2 | 0 | 1 |
Bone pain | 2 | 1 | 0 |
Constipation | 2 | 1 | 1 |
Dehydration | 2 | 1 | 0 |
Fatigue | 2 | 4 | 3 |
Glucose tolerance impaired | 2 | 1 | 0 |
Headache | 2 | 0 | 1 |
↓ Hemoglobin | 2 | 0 | 2 |
Hyperglycemia | 2 | 0 | 1 |
Hypoalbuminemia | 2 | 0 | 1 |
Hypotension | 2 | 1 | 0 |
Leukopenia | 2 | 1 | 0 |
Musculoskeletal disorder | 2 | 0 | 1 |
Nausea | 2 | 1 | 0 |
↓ Neutrophil count | 2 | 1 | 1 |
Pain in extremity | 2 | 1 | 0 |
Tooth infection | 2 | 0 | 1 |
Includes all grade 2 and above toxicities considered possible, likely, or probably related to cilengitide.