FIG.6.
Dose-response for 17α-E2 and memory performance. Data were analyzed by one-way ANOVA with post-hoc test (Fisher LSD). The dashed line at the exploration ratio of 0.5 indicates chance level performance (rats spent equal amount of time around objects at old and new locations). A. Object Placement (OP). ANOVA was significant, F 3, 30=4.06, p<0.015, and 5μg/kg of E2 enhanced OP memory (p<0.0019). B. Object Recognition (OR). ANOVA was significant, F 4, 38=2.763, p<0.041 and both 1μg/kg (p<0.013) and 2ug/kg (p<0.02) of E2 enhanced memory. Entries are means ± SEMs. *p<0.05.