Figure 1.
QuEST’s representation of ChIP-Seq data using density profiles.. (A) GABP ChIP-Seq reads from the promoter and CpG island of the Nitric oxide synthase interacting protein gene. Hypothetical GABP binding in five cells and the corresponding DNA fragments with sequencing reads. Below, actual read data. Forward reads are displayed as small blue bands and reverse reads as small maroon bands. (B) Forward (blue) and reverse (maroon) Read Density Profiles derived from the read data contribute to the Combined Density Profile (orange). The zero x-coordinate corresponds to coordinate 54775300 of human Chromosome 19, NCBI build 36.