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Progression-free survival in high risk gastrointestinal stromal tumor (GIST) patients treated with downsizing tyrosine kinase inhibitor (TKI) until function-sparing surgery was expected (mean duration 4.9 months) prior to R0 resection of the primary followed by adjuvant TKI, compared with historical controls treated with surgery only (**p < 0.01). Start date for survival was the date of diagnosis
