Table 2.

Frequency of Risk Allele and Association with Prostate Cancer by Disease Subgroup and Case-only testing.

			OR(95% CI)a Risk Allele Frequency	OR(95% CI)a Risk Allele Frequency
SNP	Chr. Gene	Allele Tested	Advanced Cases 961 ca/2359 co	Non-Advanced Cases 1600 ca/2359 co	Phetb
rs721048	2p15 EHBP1	A	1.00(0.82–1.21) 0.09	1.11(0.94–1.30) 0.09	0.33
rs2660753	3p12.1	T	1.15(1.01–1.30) 0.26	1.06(0.96–1.19) 0.26	0.26
rs9364554	6q25.3 SLC22A3	T	1.06(0.93–1.21) 0.22	1.12(0.99–1.25) 0.22	0.53
rs10486567	7p15.2 JAZF1	G	1.13(0.99–1.29) 0.47	1.31(1.17–1.46) 0.47	0.088
rs6465657	7q21.3 LMTK2	C	0.95(0.83–1.08) 0.75	1.04(0.93–1.17) 0.75	0.17
rs10993994	10q11.23 MSMB	T	1.07(0.96–1.20) 0.47	1.16(1.06–1.27) 0.47	0.19
rs12769019	10q26.13 CTBP2	G	1.16(1.00–1.36) 0.15	1.08(0.94–1.23) 0.15	0.36
rs7931342	11q13.2	G	1.17(1.04–1.32) 0.45	1.10(1.00–1.22) 0.45	0.37
rs11649743	17q12 HNF1B	G	1.14(0.99–1.32) 0.80	1.10(0.98–1.25) 0.80	0.69
rs4430796	17q12 HNF1B	A	1.16(1.03–1.30) 0.53	1.15(1.05–1.27) 0.53	0.88
rs1859962	17q24.3	G	1.00(0.89–1.12) 0.42	1.07(0.97–1.18) 0.42	0.27
rs2735839	19q13 KLK2/3	G	1.03(0.91–1.17) 0.70	1.09(0.98–1.21) 0.70	0.33
rs5945572	Xp11.22 NUDT10/11	A	1.27(1.04–1.55) 0.19	1.31(1.11–1.54) 0.19	0.84

^aORs adjusted for age(quintiles)-ethnicity strata, and genome-wide European ancestry (African Americans, Latinos and Native Hawaiians)

^bP_het = p value for heterogeneity (advanced vs. non-advanced)