Table 1.
Clinical data as well as DTI and FDG PET asymmetries of the thalamus.
| Patient No./affected side |
Gender/ age (years) |
Age at seizure onset (years) |
Angioma location on T1-Gad MRI |
PET location of hypometabolism |
FSIQ | Affected hand fine motor function scores |
FA-AI (%) |
MD-AI (%) |
FDG-AI (%) |
|---|---|---|---|---|---|---|---|---|---|
| 1/L | F/3.1 | 2 | LOpostT | LTP(O) | 112 | 2 | −0.8 | 1.4 | 1.2 |
| 2/L | F/3.4 | No epilepsy | LPO | LT(P) | 104 | 1 | −3.6 | -0.7 | 5.0 |
| 3/L | F/8.9 | 0.3 | LO(T) | LTPO | 82 | 3 | −10.6 | 5.7 | −12.5 |
| 4/L | M/3.9 | 3.5 | LO(P) | LO(T,P) | 110 | 2 | −10.5 | 0.7 | −5.2 |
| 5/L | F/8.1 | 0.2 | LTPO(F) | LTPO | 55 | 3 | −1.8 | 8.6 | −23.7 |
| 6/L | M/9.7 | 8 | LP | LTO | 87 | 3 | −1.0 | 0.6 | −0.2 |
| 7/L | M/9.3 | 0.3 | LTPO(F) | LTPO(F) | 73 | 3 | −14.9 | 3.5 | −15.8 |
| 8/L | F/3.8 | 0 | LF | FTP | 91 | 3 | −2.3 | 1.4 | −7.7 |
| 9/L | F/6.0 | 0.3 | LTPO | LTPO(F) | 69 | 3 | −2.9 | 4.7 | −18.9 |
| 10/L | F/3.5 | 2 | LP | LP(T) | 91 | 2 | −2.5 | 0.6 | −8.9 |
| 11/L | M/3.3 | 0.4 | LFTPO | LFTPO | 85 | 3 | 3.8 | 4.2 | −16.4 |
| 12/L | F/4.1 | 0.5 | None | LTPO | 87 | 2 | −1.7 | 0.4 | −0.2 |
| 13/L | M/8.2 | 0.6 | LPO | LP(T,O) | 100 | 3 | −2.6 | −1.0 | −2.4 |
| 14/R | M/8.9 | 1.8 | RTPO | RTPO | 76 | 3 | 8.3 | −1.2 | −3.8 |
| 15/R | F/11.3 | 1.7 | RP | RP | 57 | 3 | 2.2 | −0.4 | −9.0 |
| 16/R | M/12.4 | n.a. | RFTpostPmedO | RFPO | 47 | 3 | 1.9 | 1.4 | −26.7 |
| 17/R | F/3.6 | 0.8 | RsupP | RP | 128 | 2 | 5.9 | 0.0 | −7.2 |
| 18/R | M/6.3 | 0.8 | RFTPO | RO(T) | 55 | 1 | −4.5 | 2.7 | 0.6 |
| 19/R | M/3.0 | 0.5 | RTPO | RPO | 92 | n.a. | −5.1 | 0.5 | −7.9 |
| 20/R | F/9.5 | 0.7 | RFTPO | RFTPO | 60 | 3 | 11.8 | 5.6 | −30.4 |
| Mean | 6.5 | 1.4 | 83 | −1.54 | 1.94 | −9.5 | |||
| (SD) | (3.1) | (1.9) | (22) | (6.3) | (2.6) | (9.8) | |||
Note: L, left; R, right; n.a., not available; F, frontal; T, temporal; P, parietal; O, occipital; post, posterior; med, medial; sup, superior; T1-Gad, postgadolinium T1 weighted images; MRI, magnetic resonance imaging; PET, positron emission tomography; Letters in parentheses mean that only small areas of the indicated lobes were affected. FSIQ, full-scale IQ; FA, fractional anisotropy; MD, mean diffusivity; FDG, 2-deoxy-2[18F]fluoro-D-glucose; AI, asymmetry index (negative AIs represent lower values ipsilateral to the angioma); SD, standard deviation. Fine motor functions scores: 1: normal, 2: borderline, 3: impaired.