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Identification of De Novo t(8;11) in Sperm
Results of der(11)t(8;11) PCR on sperm DNA from a healthy East Asian male. Nested PCR primers were used to generate t(8;11)-specific translocation products using 250 ng aliquots of sperm DNA as template (1–16). The arrow indicates the expected size of the der(11)t(8;11) junction fragment, and the stars denote two der(11)t(8;11)-positive reactions. The positive reactions were sequenced and correspond to the expected der(11)t(8;11) sequences.
