Table 1.

Phenotypes of Patients with Supernumerary der(22)t(8;22)

Case	t(8;22) Inheritance	Sex	Age (Yrs)	Birth Weight	Growth	Ears	Extremities	Genitalia	Development/ IQ	Reference
1a	maternal	M	18	normal	normal	prominent	clinodactyly	normal	50	Sanchez et al.31
2a	maternal	F	29	normal	normal	prominent, low set	clinodactyly	normal	59	Sanchez et al.31
3b	maternal	M	12	-	normal	-	clinodactyly	ectopic testes	50	Rethore et al.32
4b	maternal	M	10	-	normal	-	clinodactyly	-	60	Rethore et al.32
5	paternal	M	16	-	normal	-	clinodactyly	ectopic testes	70	Rethore et al.32
6	maternal	M	-	-	-	-	-	-	-	Rethore et al.32
7	maternal	M	5	-	-	preauricular pit, low set	-	cryptorchidism	no speech at 5 yrs of age	Rethore et al.32
8	paternal	M	5.5	normal	weight, length < 3%	preauricular pit, atretic ear	clinodactyly	normal	moderate speech and language delayc	Mark et al.26
9	-	M	43	-	-	large	-	cryptorchidism	50–60	Helbig et al.27
10	paternal	F	10	-	-	preauricular pit	-	-	educational assistance via math resource room	Gotter et al.23
11	maternal	M	3.5	normal	normal	large	clinodactyly	-	63d	This study

“-” indicates unknown data.

^a,bSiblings.

^cNo formal testing.

^dMullen Scales of Early Learning.