Table 2.
Hemodynamic and angiographic measures before- and after treatment
| Before treatment |
After treatment |
p value |
|
|---|---|---|---|
| Control (n = 7) | |||
| HR, beats/min | 84 ± 2 | 84 ± 2 | 0.851 |
| Mean AoP, mm Hg | 73 ± 3 | 76 ± 4 | 0.668 |
| LV EDP, mm Hg | 14 ± 1 | 15 ± 1 | 0.356 |
| LV EDV, ml | 60 ± 1 | 63 ± 1 | 0.006 |
| LV ESV, ml | 38 ± 1 | 44 ± 1 | <0.001 |
| LV EF, % | 36 ± 1 | 31 ± 1 | <0.001 |
| Wall stress, g/cm2 | 54 ± 1 | 57 ± 3 | 0.341 |
| τ, ms | 44 ± 1 | 54 ± 1 | <0.001 |
| Atenolol (n = 6) | |||
| HR, beats/min | 81 ± 3 | 85 ± 2 | 0.234 |
| Mean AoP, mm Hg | 75 ± 4 | 73 ± 3 | 0.544 |
| LV EDP, mm Hg | 14 ± 1 | 13 ± 1 | 0.137 |
| LV EDV, ml | 60 ± 2 | 60 ± 2 | 0.771 |
| LV ESV, ml | 37 ± 1 | 36 ± 1 | 0.111 |
| LV EF, % | 38 ± 1 | 39 ± 1 | 0.137 |
| Wall stress, g/cm2 | 61 ± 6 | 55 ± 5 | 0.215 |
| τ, ms | 45 ± 1 | 42 ± 2 | 0.195 |
| Metoprolol CR/XL (n = 7) | |||
| HR, beats/min | 84 ± 3 | 82 ± 2 | 0.594 |
| Mean AoP, mm Hg | 75 ± 3 | 77 ± 4 | 0.567 |
| LV EDP, mm Hg | 15 ± 1 | 12 ± 1 | 0.007 |
| LV EDV, ml | 62 ± 2 | 61 ± 3 | 0.188 |
| LV ESV, ml | 39 ± 2 | 35 ± 2 | 0.002 |
| LV EF, % | 37 ± 1 | 43 ± 1 | <0.001 |
| Wall stress, g/cm2 | 58 ± 3 | 48 ± 3 | 0.005 |
| τ, ms | 45 ± 3 | 36 ± 1 | 0.008 |
HR = Heart rate; AoP = aortic pressure; EDP = end-diastolic pressure; EDV = end-diastolic volume; ESV = end-systolic volume.