Fig. 2. Scgn expression in mouse and primate embryos at mid-gestation.

(A,A₁) Scgn⁺ organ systems in mouse embryo. Doublecortin, a microtubule-associated protein widely expressed by migrating cells in the developing nervous system (Gleeson et al., 1999), was used to reveal anatomical boundaries of various organs. (B,B₁) Scgn⁺ organs in the grey mouse lemur embryo. Open rectangles in A and B denote the general location of high-resolution photomicrographs in B₁-C₁. (B₁) Scgn immunoreactivity decorates putative enteroendocrine cells (Mulder et al., 2009b) at the base of gastric pits formed in the stomach of lemur embryos. (C,C₁) Prospective sensory neurons in the dorsal root ganglion (DRG) of the lemur (arrows, C₁) but not mouse (C) express scgn. Abbreviations are listed in Supporting Table 1. Scale bars = 30 μm (B₁), 150 μm (C,C₁), 0.5 mm (A,B).