Table 1.

SNPs reliably associated with aBMD in genome-wide association studies and analyzed in association with pQCT measures in this current study

SNP	Location	Gene	Trait	P value	Ref.
rs9594738	13q14	RANKL	Lumbar spine or hip BMD	1.9 × 10−8	Styrkarsdottir et al. (5)
rs7524102	1p36		Lumbar spine or hip BMD	5.0 × 10−16	Styrkarsdottir et al. (5)
rs3736228	11q13	LRP5	Lumbar spine BMD	6.3 × 10−12	Richards et al. (2)
rs6993813	8q24	OPG	Lumbar spine or hip BMD	3.3 × 10−11	Styrkarsdottir et al. (5)
rs4355801	8q24	OPG	Lumbar spine BMD	7.6 × 10−10	Richards et al. (2)
rs3018362	18q21	RANK	Hip BMD	5.4 × 10−8	Styrkarsdottir et al. (6)
rs1038304	6q25	ESR1	Lumbar spine or hip BMD	5.3 × 10−9	Styrkarsdottir et al. (5)
rs1513670	17q21	SOST	Hip BMD	2.1 × 10−8	Styrkarsdottir et al. (6)
rs2010281	14q32	MARK3	Hip BMD	1.8 × 10−9	Styrkarsdottir et al. (6)

SNPs are ordered by effect size as reported by the Genetic Factors of Osteoporosis Consortium (8) or Ref. 6 for rs3018362.