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. Author manuscript; available in PMC: 2010 Aug 9.

Published in final edited form as: Aging Cell. 2009 Apr 9;8(3):331–338. doi: 10.1111/j.1474-9726.2009.00480.x

Fig. 2 — (A) Treatment of lines 2 and 11 with 1 mM paraquat resulted in a significant reduction of lifespan in both lines (p<0.0001). Males show a greater sensitivity to paraquat. Line 2 females exhibit marked resistance. (B) Treatment with paraquat resulted in an increase in mutation frequency at the lacZ transgene locus (p<0.0001). Mutation frequencies are lower in males than females but elevated more after paraquat exposure, which correlates positively with effects on lifespan.

Fig. 2 — (A) Treatment of lines 2 and 11 with 1 mM paraquat resulted in a significant reduction of lifespan in both lines (p<0.0001). Males show a greater sensitivity to paraquat. Line 2 females exhibit marked resistance. (B) Treatment with paraquat resulted in an increase in mutation frequency at the lacZ transgene locus (p<0.0001). Mutation frequencies are lower in males than females but elevated more after paraquat exposure, which correlates positively with effects on lifespan.