Table 4.
Bivariate lod scores > 2.95 (suggestive) for which QTL effects for both traits (q21 and q22) were at least suggestive (P < 0.001).
Chromosome | Position (MB)1 | Trait1 | Trait2 | Lod2 | P-Value3 | P-Value | |
---|---|---|---|---|---|---|---|
q12 | q22 | ρq | |||||
1 | 16–19 | LDL-C | T2D | 4.41 | 0.000348 | 0.00000814 | 0.00180 |
2 | 81–101 | TG | T2D | 4.23 | 0.000377 | 0.00000515 | 0.000755 |
2 | 232–239 | HDL-C | TG | 3.07 | 0.000138 | 0.000164 | 0.000389 |
2 | 234–240 | TG | T2D | 4.27 | 0.000192 | 0.0000522 | 0.00284 |
3 | 137–147 | LDL-C | BMI | 4.25 | 0.000372 | 0.000201 | 0.0364 |
5 | 18–32 | HDL-C | TG | 3.92 | 0.000147 | 0.000243 | 0.00425 |
13 | 28–34 | TC | BMI | 3.29 | 0.000220 | 0.0000578 | 0.000529 |
1-lod drop support interval in megabases, Build 37.1
Significant (>4.31, bold) and near-significant (>4.00, italics) univariate lod scores.
Significant (<0.00005, bold) and near-significant (<0.0001, italics) P-values.