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β-catenin siRNA suppression of IGF-I-promoted oligodendrocytes survival. Oligodendrocytes were pre-treated with β-catenin siRNA (βCat) or a negative control siRNA (neg siRNA), as well as 100 ng/ml of IGF-I, as previously described in Figure 9. Values represent mean ± SE of 4 samples. *, P < 0.001, compared to non-IGF-I treated controls. ^, P < 0.01, compared to IGF-I treated cells that were pre-transfected with negative control siRNA.
