Figure 1.

Pedigree structures for families recruited into the T1DGC. Dark fill represents a family member with type 1 diabetes; no fill, unaffected; and crosshatch may be either. The dotted line indicates the minimum inclusion criteria for family recruitment into the T1DGC collection. The maximal included pedigree structure includes 5 affected and 2 unaffected siblings in affected sibling pair families; no additional siblings were collected in trio families. All recruited family members were typed for all HLA loci.