Skip to main content
. Author manuscript; available in PMC: 2011 Jul 12.
Published in final edited form as: J Comb Chem. 2010 Jul 12;12(4):566–570. doi: 10.1021/cc100054u

Table 3.

Substituted piperidine products obtained

Entry R Obtained MW Yield (%) a
8a graphic file with name nihms212294t5.jpg 449 (MH+) 76
8b graphic file with name nihms212294t6.jpg 463 (MH+) 72
8c graphic file with name nihms212294t7.jpg 521 (MH+) 68
8d graphic file with name nihms212294t8.jpg 499 (MH+) 82
8e graphic file with name nihms212294t9.jpg 535 (MH+) 85
8f graphic file with name nihms212294t10.jpg 430 (MH+) 74
8g graphic file with name nihms212294t11.jpg 464 (MH+) 79
8h graphic file with name nihms212294t12.jpg 432 (MH+) 72
8i graphic file with name nihms212294t13.jpg 480 (MH+) 80
a

Yields based on the weight of purified product and are relative to the initial loading of the resin. The purity of the purified compounds is higher than 95% for all the compounds. The purity was estimated on analytical traces at λ= 214 nm and 254 nm.