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Mean concentrations (± 95% confidence interval) of methylenedioxymethamphetamine (MDMA) and its metabolite methylenedioxyamphetamine (MDA) in mouse striatum after 10, 20 or 40 mg/kg MDMA, i.p. (n=5 for each timepoint). Filled circles depict mdr1a +/+ mice and open circles depict mdr1a −/− mice.
