Skip to main content
. Author manuscript; available in PMC: 2010 Aug 9.
Published in final edited form as: J Infect Dis. 2009 Apr 1;199(7):1019–1028. doi: 10.1086/597210

Figure 4.

Figure 4

Enrichment of CD27− memory T cells and diminished expression of CD127 in CD4+ T cell subsets from HIV-infected persons. Whole blood was analyzed by staining cells for expression of CD3, CD4, CD45RO, CD27, and CD127. Data are shown for 9 healthy control subjects (lined bars), 11 viremic HIV-positive donors (HIV RNA oad, >400 copies/mL; empty bars), and 6 aviremic HIV-positive donors (HIV RNA load, ≤400 copies/mL; crosshatched bars). Statistical analyses comparing cells from HIV-positive donors and control subjects were performed with Kruskal-Wallis and Mann-Whitney U tests. A, Percentages of CD27+CD45RO− naive, CD27+CD45RO+ memory, CD27−CD45RO+ memory, and CD27−CD45RO− terminal memory cells in the CD4+CD3+ T cell subset. *P < .02. B, Percentage of cells expressing CD127. *P < .05. C, Mean fluorescence intensity (MFI) of CD127 expression in CD4+ T cell subsets. *P < .05 and **P < .005. In C and B, insufficient numbers of events were collected to permit analyses of CD127 expression on terminal memory cells from the aviremic HIV-positive patient population.