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Fig. 4. Effect of dominant-negative sortilin lacking its cytoplasmic domain in COS-7 cells immunostained with anti-cathepsin B antibody. While anti-cathepsin B antibody produced a punctate staining in the cytoplasm of non-transfected cells (not shown), the truncated construct (B and C) had no effects on the staining pattern of anti-cathepsin B antibody (A and C). Scale bar = 20 µm.
