Fig. 4. Th2 cytokine levels are down-regulated in the lungs of Gal-3 KO mice in response to chronic allergen challenge.

Key Th1 (IL-2 and IFN-γ) and Th2 (IL-4, IL-5 and IL-13) cytokine levels in lung lysates of control and chronic allergen-challenged WT and Gal-3 KO mice (n = 5–8/group) was determined by CBA. Results were expressed as mean ± SE of pg/mg protein for each cytokine. *p < 0.05 compared with WT PBS mice. **p <0.05 compared to WT OVA.