TABLE 2.
Demographic Characteristics of Bipolar Disorder Patients Participating in STEP-BD Who Experienced a New-Onset Depressive Episode, by Drug Use Disorder History
| Variable | Drug Use Disorder History |
Analysis |
||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Never (N=1,528) | Past (N=468) | Current (N=158) | All (N=2,154) | χ2 | p | |||||||||
| Total N | N | % | Total N | N | % | Total N | N | % | Total N | N | % | |||
| Gender | 1,528 | 468 | 158 | 2,154 | 13.10 | 0.001 | ||||||||
| Male | 595 | 38.9 | 201 | 42.9 | 84 | 53.2 | 880 | 40.9 | ||||||
| Female | 933 | 61.1 | 267 | 57.1 | 74 | 46.8 | 1,274 | 59.1 | ||||||
| Bipolar type | 1,528 | 468 | 158 | 2,154 | 7.14 | 0.028 | ||||||||
| Bipolar I disorder | 1,036 | 67.8 | 331 | 70.7 | 122 | 77.2 | 1,489 | 69.1 | ||||||
| Bipolar II disorder | 492 | 32.2 | 137 | 29.3 | 36 | 22.8 | 665 | 30.9 | ||||||
| Race | 1,528 | 468 | 158 | 2,154 | 10.16 | 0.006 | ||||||||
| White | 1,378 | 90.2 | 445 | 95.1 | 143 | 90.5 | 1,966 | 91.3 | ||||||
| Non-white | 150 | 9.8 | 23 | 4.9 | 15 | 9.5 | 188 | 8.7 | ||||||
| Married | 1,434 | 459 | 157 | 2,050 | 12.94 | 0.002 | ||||||||
| Yes | 569 | 39.7 | 164 | 35.7 | 41 | 26.1 | 774 | 37.8 | ||||||
| No | 865 | 60.3 | 295 | 64.3 | 116 | 73.9 | 1,276 | 62.2 | ||||||
| Employed | 1,434 | 459 | 157 | 2,050 | 0.15 | 0.930 | ||||||||
| Yes | 624 | 43.5 | 204 | 44.4 | 68 | 43.3 | 896 | 43.7 | ||||||
| No | 810 | 56.5 | 255 | 55.6 | 89 | 56.7 | 1,154 | 56.3 | ||||||
| Current anxiety | 1,528 | 468 | 158 | 2,154 | 51.56 | <0.001 | ||||||||
| Yes | 550 | 36.0 | 235 | 50.2 | 91 | 57.6 | 876 | 40.7 | ||||||
| No | 978 | 64.0 | 233 | 49.8 | 67 | 42.4 | 1,278 | 59.3 | ||||||
| Rapid cycling in past year | 1,528 | 468 | 158 | 2,154 | 7.71 | 0.021 | ||||||||
| Yes | 723 | 47.3 | 252 | 53.8 | 83 | 52.5 | 1,058 | 49.1 | ||||||
| No | 805 | 52.7 | 216 | 46.2 | 75 | 47.5 | 1,096 | 50.9 | ||||||
| History of suicide attempt | 1,473 | 459 | 156 | 2,088 | 24.82 | <0.001 | ||||||||
| Yes | 546 | 37.1 | 223 | 48.6 | 76 | 48.7 | 845 | 40.5 | ||||||
| No | 927 | 62.9 | 236 | 51.4 | 80 | 51.3 | 1,243 | 59.5 | ||||||
| Total N | Mean | SD | Total N | Mean | SD | Total N | Mean | SD | Total N | Mean | SD | F | p | |
| Age | 1,528 | 41.08 | 12.77 | 468 | 39.42 | 10.49 | 158 | 34.37 | 10.73 | 2,154 | 40.23 | 12.30 | 23.34 | <0.0001 |
| Age at onset | 1,488 | 17.72 | 9.05 | 465 | 14.48 | 6.54 | 156 | 14.81 | 7.23 | 2,109 | 16.79 | 8.55 | 30.83 | <0.0001 |
| Age at onset of mania | 1,445 | 22.56 | 10.52 | 444 | 18.32 | 7.97 | 152 | 18.65 | 8.12 | 2,041 | 21.34 | 10.03 | 37.78 | <0.0001 |
| Age at onset of depression | 1,415 | 18.55 | 9.61 | 442 | 15.56 | 7.29 | 150 | 15.55 | 7.43 | 2,007 | 17.67 | 9.10 | 23.21 | <0.0001 |
| Depressed days/year | 1,492 | 51.01 | 28.58 | 461 | 52.92 | 28.68 | 150 | 51.20 | 26.11 | 2,103 | 51.44 | 28.42 | 0.79 | 0.452 |
| Anxious days/year | 1,468 | 39.37 | 34.10 | 459 | 42.43 | 34.17 | 149 | 44.93 | 34.27 | 2,076 | 40.44 | 34.16 | 3.33 | 0.036 |
| Irritable days/year | 1,475 | 34.62 | 31.04 | 458 | 38.09 | 30.89 | 150 | 41.10 | 32.49 | 2,083 | 35.85 | 31.16 | 4.80 | 0.008 |
| Elevated days/year | 1,474 | 18.00 | 19.97 | 458 | 22.46 | 21.12 | 150 | 24.48 | 21.39 | 2,082 | 19.45 | 20.45 | 14.14 | <0.0001 |