Fig. 3.
Immunohistochemistry for c-Kit and endothelial nitric oxide synthase (eNOS) in the adventitia of the venous limb of the AV fistula. A: c-Kit-positive immunoreactivity (green) in adventitial microvessels, exhibiting lumina, some of which are marked by asterisks. B: eNOS-positive immunoreactivity (red) in the same adventitial microvessels. C: merged image showing combined immunostaining (yellow) in all 4 adventitial microvessels, as indicated by white arrows. Bottom: Western blot analysis demonstrating expression of eNOS in the venous limb of the AV fistula and sham-operated rats; equivalency of loading of the gel was assessed by immunostaining for β-actin.