Table 2.
Multivariate Logistic regression Analyses: BMI overall and by Gender
| Variables | Overall (n=523) |
Men (n=276) |
Women (n=247) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Cases (n=253) | Controls (n=270) | OR* (95% CI) | Cases (n=132) | Controls (n=144) | OR* (95% CI) | Cases (n=121) | Controls (n-126) | OR* (95% CI) | |
| BMI at age 25c | |||||||||
| Under/normal | 155 (66%) | 158 (78%) | 1.00 | 68 (56%) | 56 (62%) | 1.00 | 87 (76%) | 102 (90%) | 1.00 |
| Overweight | 58 (25%) | 40 (20%) | 1.53 (0.93–2.53) | 41 (34%) | 32 (35%) | 1.17 (0.63–2.16) | 17 (15%) | 8 (7%) | 2.58 (1.03–6.47) |
| Mildly obese | 17 (7%) | 3 (2%) | 4.29+ (1.63–11.3) | 8 (7%) | 1 (1%) | 5.13+ (1.20–21.9) | 9 (8%) | 2 (2%) | 4.07+ (1.05–15.8) |
| Moderately/severely obese | 5 (2%) | 3 (2%) | 4 (3%) | 2 (2%) | 1 (1%) | 1 (1%) | |||
| p-trend=0.002 | p-trend=0.07 | p-trend=0.008 | |||||||
| BMI at age 25 (continuous) | 1.09 (1.03–1.15) | 1.09 (1.01–1.19) | 1.08 (1.00–1.16) | ||||||
| BMI at age 40c | |||||||||
| Under/normal | 73 (40%) | 101 (55%) | 1.00 | 23 (23%) | 46 (45%) | 1.00 | 50 (60%) | 55 (66%) | 1.00 |
| Overweight | 62 (34%) | 68 (37%) | 1.30 (0.79–2.14) | 50 (50%) | 45 (44%) | 2.13 (1.10–4.12) | 12 (14%) | 23 (28%) | 0.59 (0.25–1.38) |
| Mildly obese | 28 (15%) | 10 (5%) | 3.83 (1.69–8.68) | 19 (19%) | 7 (7%) | 4.89 (1.76–13.6) | 9 (11%) | 3 (4%) | 3.26 (0.75–14.2) |
| Moderately/severely obese | 22 (12%) | 6 (3%) | 5.12 (1.92–13.6) | 9 (9%) | 4 (4%) | 4.35 (1.19–15.9) | 13 (16%) | 2 (2%) | 7.19 (1.43–36.2) |
| p-trend<0.001 | p-trend=0.001 | p-trend=0.02 | |||||||
| BMI at age 40 (continuous) | 1.11 (1.05–1.16) | 1.12 (1.05–1.21) | 1.09 (1.02–1.17) | ||||||
| BMI at diagnosis/interview | |||||||||
| Under/normal | 71 (28%) | 103 (40%) | 1.00 | 26 (20%) | 46 (33%) | 1.00 | 45 (37%) | 57 (48%) | 1.00 |
| Overweight | 95 (38%) | 105 (40%) | 1.28 (0.83–1.97) | 61 (47%) | 66 (47%) | 1.50 (0.81–2.76) | 34 (28%) | 39 (33%) | 1.11 (0.59–2.10) |
| Mildly obese | 51 (20%) | 37 (14%) | 2.12 (1.24–3.65) | 28 (21%) | 22 (16%) | 2.22 (1.04–4.75) | 23 (19%) | 15 (13%) | 2.11 (0.96–4.67) |
| Moderately/severely obese | 35 (14%) | 16 (6%) | 3.09 (1.56–6.13) | 16 (12%) | 7 (5%) | 3.79 (1.34–10.7) | 19 (16%) | 9 (8%) | 2.65 (1.06–6.64) |
| p-trend<0.001 | p-trend=0.004 | p-trend=0.01 | |||||||
| BMI at diagnosis/interview (continuous) | 1.08 (1.04–1.12) | 1.11 (1.05–1.17) | 1.06 (1.02–1.11) | ||||||
*
Adjusted for gender, ethnicity, age, and agrochemical exposure
c
Number of cases and controls in these categories are less than the total number for the study due to exclusion of subjects younger than the age cut-points
+
OR calculated for mildly obese and moderately/severely obese combined due to small number of individuals in these categories