Table 3.
Weight gain: Multivariate* regression among participants age 45+
| Weight change from: | Cases (%) | Controls | OR *(95% CI) |
|---|---|---|---|
| Age 25 to age 40d | |||
| Lost >=0.1 kg/yr | 4 (3%) | 12 (8%) | 0.38 (0.09–1.54) |
| No change (0+/−0.1 kg/yr) | 13 (9%) | 22 (14%) | 1.00 |
| Gain 0.1 – 0.5 kg/yr | 49 (35%) | 71 (46%) | 1.07 (0.48–2.39) |
| Gain 0.5 – 1 kg/yr | 33 (24%) | 31 (20%) | 1.62 (0.67–3.92) |
| Gain >1 kg/yr | 40 (29%) | 18 (12%) | 3.63 (1.46–9.04) |
| Mean change kg/yr | 0.78 | 0.44 | P < 0.001 |
| Age 25 to diagnosis/interviewc | |||
| Lost >=0.1 kg/yr | 6 (4%) | 7 (5%) | 1.02 (0.27–3.88) |
| No change (0+/−0.1 kg/yr) | 17 (12%) | 23 (15%) | 1.00 |
| Gain 0.1 – 0.5 kg/yr | 48 (35%) | 73 (47%) | 0.85 (0.41–1.80) |
| Gain 0.5 – 1 kg/yr | 53 (38%) | 40 (26%) | 1.78 (0.81–3.90) |
| Gain >1 kg/yr | 15 (11%) | 12 (8%) | 1.66 (0.58–4.79) |
| Mean change kg/yr | 0.52 | 0.42 | P = 0.05 |
| Age 40 to diagnosis/interviewd | |||
| Lost >=0.1 kg/yr | 31 (22%) | 17 (11%) | 2.43 (0.99–5.96) |
| No change (0+/−0.1 kg/yr) | 21 (15%) | 29 (18%) | 1.00 |
| Gain 0.1 – 0.5 kg/yr | 43 (30%) | 51 (32%) | 1.26 (0.60–2.63) |
| Gain 0.5 – 1 kg/yr | 28 (20%) | 44 (28%) | 0.86 (0.39–1.89) |
| Gain >1 kg/yr | 20 (14%) | 17 (11%) | 1.57 (0.61–4.04) |
| Mean change kg/yr | 0.30 | 0.43 | P = 0.2 |
a
Adjusted for age, sex, ethnicity, agrochemical exposure, family hx, and weight at age 25/40