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. 2010 Jan 21;115(12):2500–2507. doi: 10.1182/blood-2009-08-238972

Figure 5.

Figure 5

PfPI3K inhibition stalls parasite growth. Parasite cultures in complete medium (A,C) or Ile medium (B,D) were incubated with DMSO/MeOH (control), indicated concentrations of wortmannin (A-B), LY294002 (C-D), or 30μM pepstatin A (Peps). Parasite growth was monitored by counting the parasite infected erythrocytes every 48 hours, the data obtained after 4 (C-D) or 6 (A-B) days of treatment are shown. The percentage growth of parasite in drug-treated cultures compared with control (100%) is indicated. Error bars represent SEM.