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. Author manuscript; available in PMC: 2010 Aug 9.
Published in final edited form as: Shock. 2009 Apr;31(4):376–381. doi: 10.1097/SHK.0b013e3181862279

Figure 2. Lung pathology after pulmonary contusion is dependent on the TLR4 pathway.

Figure 2

Injured lungs were formalin fixed, stained and analyzed by an experienced pathologist. Lung sections of the contusion are shown (100× magnification) at 24 hours after injury. Hemorrhage is evident in all injuries (left panels) and masked by red filter (right panels) to highlight neutrophil staining. Septal edema and neutrophil infiltration is reduced in TLR4 and MyD88 deficient mice when compared to WT. Specimens shown are representative of lung injuries in at least 3 animals/genotype.