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. Author manuscript; available in PMC: 2011 Jul 11.
Published in final edited form as: Behav Brain Res. 2010 Feb 13;210(2):155–163. doi: 10.1016/j.bbr.2010.02.016

Figure 3.

Figure 3

Peptide concentrations in the dorsal striatum for ICR, HR and M16 mice. HPLC analysis of tissue samples from dorsal striatum in HR, M16 and ICR mice was performed to measure tissue concentrations of DA, DOPAC, HVA, NE, 5HT and 5HIAA. Peptide concentrations for DA (F(2,92)=60.53, p<0.001), DOPAC (F(2,92)=34.34, p<0.001), HVA (F(2,92)=61.98, p<0.001), 5HT (F(2,92)=6.61, p<0.01) and 5HIAA (F(2,92)=7.37, p<0.01) were significantly higher in HR mice than in M16 or ICR mice. There were no differences in NE concentrations among the strains. 5HIAA concentrations were significantly higher in female compared to male mice across all three strains (F(1,92)=5.40, p<0.05). Female HR mice had lower, while M16 and ICR females had higher, DOPAC concentrations (F(2,92)=4.47, p<0.05) than their male counterparts. Data are presented as mean +/- SEM.