Table 2.

LV function and hemodynamic measurements during post-MI LV remodeling. Significant increases in LV volumes indicate progressive LV dilation during infarct healing. These are accompanied by decreased EF, and decreased wall thickness of infarcted myocardium (*P< 0.05 vs. Day 1, ^§P < 0.05 vs. Day 7).

	Day 1	Day 7	Day 14	Day 28
N	4	3	5	5
Body Weight (g)	21.3 ± 0.5	23.5 ± 0.9	23.6 ± 0.7	25.2 ± 0.8*
EDV (μL)	47.4 ± 4.9	58.9 ± 1.3	71.2 ± 3.3*	70.7 ± 4.1*
ESV (μL)	29.4 ± 4.1	39.9 ± 2.5	52.4 ± 4.2*	52.8 ± 4.1*
EF (%)	38.3 ± 4.9	33.8 ± 3.7	27.3 ± 3.0*	24.9 ± 3.3*§
LV Mass (mg)	70.2 ± 5.6	68.1 ± 1.9	73.0 ± 1.9	81.4 ± 2.3
Remote Zone Wall Thickness (mm)	0.84 ± 0.01	0.86 ± 0.04	0.84 ± 0.03	0.94 ± 0.04
Infarct Zone Wall Thickness (mm)	0.91 ± 0.03	0.67 ± 0.04*	0.62 ± 0.03*	0.61 ± 0.02*
HR (bpm)	569 ± 12	569 ± 35	557 ± 18	567 ± 24
Respiratory Interval (ms)	606 ± 52	428 ± 23*	409 ± 17*	392 ± 34*
Minimum Respiratory Interval (ms)	411 ± 53	388 ± 24	330 ± 10	339 ± 19
Maximum Respiratory Interval (ms)	819 ± 72	506 ± 31*	487 ± 21*	471 ± 13*
Temperature (C)	35.3 ± 0.2	35.6 ± 0.4	35.9 ± 0.3	36.8 ± 0.3