Figure 3.
Flavin substituent effects on Dkcat. Reactions with IPP and (R)-[2-2H]-IPP (open and filled circles, respectively, in panel B) were carried out under pseudo-first order conditions as described in the supporting information. (A) Calculated Dkcat from the data in panel (B). (B) Hammett plots: ρ = −2.5(4) and −2.7(5) for IPP and (R)-[2-2H]-IPP, respectively.