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. 2010 Sep;51(9):2504–2515. doi: 10.1194/jlr.M001958

Fig. 2.

Fig. 2.

BBR alleviates HFD-induced fatty liver in SD rats. After BBR treatment for 16 weeks, rats were euthanized after a 14 h fast. A: Histological analysis of livers of ND-fed, vehicle-treated rats (ND group) and HFD-fed rats treated with vehicle (HFD group) or BBR (BBR+HFD group). Liver sections were stained with hematoxylin and eosin (upper panel) or with Sudan Ш (lower panel). Photographs are at 200× magnification. B: Effects of BBR on liver weight. C: Effects of BBR on hepatic TG contents. Significance was assessed by one-way ANOVA followed by Tukey's multiple comparison test. Data are mean ± SEM. *P < 0.05, **P < 0.01 versus ND; #P < 0.05, ##P < 0.01 versus HFD. BBR, berberine; HFD, high-fat diet; ND, normal diet; SD, Sprague-Dawley; TG, triglyceride.