TABLE 1.

General parameters of BBR treatment for 16 weeks and control groups

Parameter	ND	HFD	BBR+HFD
Visceral fat (g)	45.1 ± 6.0	74.7 ± 8.2a	42.7 ± 5.8b
Serum TC (mmol/l)	2.17 ± 0.13	2.81 ± 0.28a	2.02 ± 0.21b
Serum LDL-c (mmol/l)	0.54 ± 0.04	2.10 ± 0.31a	1.22 ± 0.19b
Serum TG (mmol/l)	2.01 ± 0.51	1.02 ± 0.10a	0.95 ± 0.12a
Serum ALT (IU/l)	68.0 ± 4.3	106.7 ± 15.6a	69.0 ± 6.4b
Serum AST (IU/l)	194.7 ± 17.3	239.9 ± 43.9	167.3 ± 13.8

Data are presented as mean ± SEM (n = 8). BBR, berberine; HFD, high-fat diet; ND, normal diet; TG, triglyceride; ALT, alanine transaminase; AST, aspartate aminotransferase.

^aP < 0.05 versus ND (normal diet + vehicle group).

^bP < 0.05 versus HFD (high-fat diet + vehicle group).