TABLE 1.

CD spectroscopy and derived thermodynamic parameters for apo A-IV 347S and apo A-IV 347T

	[Θ]222	Tm	n	ΔHD	ΔS
	deg-cm2-dmol−1	°C		kcal/mo/	cal/mol°K
apo A-IV 347S	26,229 ± 849	48.8 ± 0.5	8.2 ± 0.9	51.3 ± 2.8a	159.4 ± 9.0a
apo A-IV 347T	28,306 ± 2750	50.2 ± 0.2	11.2 ± 0.2	70.7 ± 1.4	218.7 ± 4.2

[Θ]₂₂₂, mean residue ellipticity at 222 nm; Tm, thermal denaturation midpoint temperature; n, denaturation curve sigmoidicity; ΔH_D, enthalpy of denaturation; ΔS, entropy of folding. Values are mean ± SE for n = 2–3 determinations.

Abbreviations: Apo, apolipoprotein; CD, circular dichroism.

^aP = 0.03 for apo A-IV 347S versus apo A-IV 347T by Student's t-test.