TABLE 1.

Plasma 7α-hydroxy-4-cholesten-3-one levels in wild-type and cyp27^−/− female mice on different treatments

Mice	Diet	7α-Hydroxy-4-cholesten-3-one
		μg/ml
WT	Control	0.053
WT	Cholestyramine	0.19
WT	Cholic acid	0.036 ± 0.014
CYP27−/−	Control	1.9 ± 0.15
CYP27−/−	Cholestyramine	3.8 ± 0.38
CYP27−/−	Cholic acid	0.49 ± 0.093

Mice were treated as indicated in the table. Data from wild-type control and cholestyramine-treated mice were received from pooled plasma from four animals per group. Individual animals analyzed per group: wild-type and CYP27^−/− cholic acid fed, n = 5, CYP27^−/− control and cholestyramine fed, n = 3.