Fig. 2.

Physical location (A) of the 16 SNPs and the gene structure of the FADS gene cluster are shown (dark blue line = physical location of genotyped SNP; light blue/pink boxes = exon/intron structure with FADS genes). Schematic overview of linkage disequilibrium patterns (B) in the 102 kb region containing the FADS gene cluster (Chr 11 q12-13), as defined by the algorithm of Gabriel et al. (31) using 224 subjects in the analysis (range of LD from high to low displayed as color ranging from dark red to white, respectively). Abbreviations: FADS, fatty acid desaturase; SNP, single nucleotide polymorphism.