Fig. 5.

Global lipidome changes. A: Ceramide heat map showing fold-increase in response to KLA. Changes are color coded; numbers indicate statistically significant fold-changes. Cer, ceramide, DH, dihydro-, Hex, hexosyl (glucosyl or galactosyl). INCR., increase from zero; DECR., decrease to zero. Acyl groups are abbreviated by the numbers of carbon atoms and double bonds per molecule. B: Increase in total ceramide (sum of individual species is shown). C: Sterol lipids heat map showing fold-increase in response to KLA. D: Increase in lanosterol. Nuc, nuclei, Mito, mitochondria, PM, plasmalemma, D.Mic, dense microsomes, Cyto, cytoplasm. Data (B and D) are mean ± SE, n = 3.