Location-specific oxysterol increases. A: Heat map. Changes are color-coded; numbers indicate statistically significant fold-changes. Nuc, nuclei; Mito, mitochondria; PM, plasmalemma; D.Mic, dense microsomes; Cyto, cytoplasm. B–E. Cholestenone (increase in mitochondria), 4-β-cholesterol (increase in mitochondria), 7-oxo-cholesterol (increase in ER). Data are mean ± SE, n = 3.