Table 5.
Associated SNP detection probability for various numbers of selected SNPs, T. δ12 = 0 with probability 0.99 and with probability 0.01, δ12 is drawn from a normal distribution with mean 0 and variance σ2
σ2 = {log(2)/2}2 = 0.12 |
σ2 = {log(2)}2 = 0.48 |
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---|---|---|---|---|---|---|---|
T | 10 | 100 | 10,000 | 10 | 100 | 10,000 | |
β1 = 0.25 | Control only(CO) | 0.005 | 0.024 | 0.275 | 0.005 | 0.025 | 0.274 |
Adaptively weighted(AW) | 0.012 | 0.044 | 0.375 | 0.012 | 0.045 | 0.374 | |
Case only(CA) | 0.000 | 0.001 | 0.249 | 0.000 | 0.001 | 0.231 | |
Weighted(W) | 0.001 | 0.022 | 0.516 | 0.000 | 0.001 | 0.496 | |
MLE | 0.001 | 0.019 | 0.512 | 0.000 | 0.001 | 0.491 | |
| |||||||
β1 = 0.69 | Control only(CO) | 0.62 | 0.85 | 0.99 | 0.62 | 0.85 | 0.99 |
Adaptively weighted(AW) | 0.73 | 0.90 | 0.99 | 0.73 | 0.90 | 0.99 | |
Case only(CA) | 0.00 | 0.16 | 0.99 | 0.00 | 0.00 | 0.99 | |
Weighted(W) | 0.52 | 0.99 | 1.00 | 0.00 | 0.09 | 1.00 | |
MLE | 0.49 | 0.98 | 1.00 | 0.00 | 0.05 | 1.00 |