Table 1.
Patient demographic details and predicted HIV-1 subtype C co-receptor tropism
| Patient demographic details | HIV-1 Co-receptor Tropism | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| No | Patient ID | Age | Sex | Time since sero-diagnosis (months) | CD4 Count (cells/mm3) | Disease Stage | WebPSSM (C-PSSM) | Geno2pheno | (ds)Kernel | |
| Score | Tropism | |||||||||
| 1. | SJNAHS01 | 33 | M | 43 | 223 | 2nd | -29.39 | R5 | R5 | R5 |
| 2. | SJNAHS02 | 53 | F | 4 | 247 | 2nd | -29.97 | R5 | R5 | R5 |
| 3. | SJNAHS03 | 30 | M | 46 | 173 | 2nd | -23.28 | R5 | R5 | R5 |
| 4. | SJNAHS04 | 37 | M | 63 | 538 | 1st | -16.09 | X4 | R5 | R5 |
| 5. | SJNAHS06 | 36 | F | 1 | 122 | 3rd | -23.32 | R5 | R5 | R5 |
| 6. | SJNAHS07 | 26 | F | 1 | 384 | 1st | -29.97 | R5 | R5 | R5 |
| 7. | SJNAHS09 | 38 | F | 1 | 356 | 3rd | -25.74 | R5 | R5 | R5 |
| 8. | SJNAHS10 | 38 | M | 105 | 438 | 3rd | -25.74 | R5 | R5 | R5 |
| 9. | SJNAHS11 | 26 | M | 15 | 594 | 1st | -29.39 | R5 | R5 | R5 |
| 10. | SJNAHS12 | 38 | M | 22 | 59 | 1st | -25.74 | R5 | R5 | R5 |
| 11. | SJNAHS13 | 36 | M | 130 | 77 | 1st | -19.35 | X4 | X4 | R5 |
| 12. | SJNAHS16 | 39 | M | 1 | 13 | 4th | -29.08 | R5 | R5 | R5 |
| 13. | SJNAHS17 | 36 | F | 1 | 75 | 1st | -29.05 | R5 | R5 | R5 |
| 14. | SJNAHS18 | 60 | M | 1 | 99 | 4th | -22.37 | R5 | R5 | R5 |
| 15. | SJNAHS19 | 40 | M | 2 | 200 | 1st | -22.37 | R5 | R5 | R5 |
Patient demographic characteristics and predicted co-receptor tropism in the South Indian cohort. CD4 count represents the value at the time of study. Co-receptor tropism was detected using C-PSSM, Geno2pheno and (ds)Kernel method. In C-PSSM a score of above -21.64 was considered predictive of X4-tropism. Disease stage according to WHO classification has been mentioned.