Table 3.
Proteins found in both the LDL fraction and the HDL fraction.
| LDL Fractions | HDL Fractions | |||
|---|---|---|---|---|
| Protein Description | Plasma Avg. Scan Count ± SEM | Serum Avg. Scan Count ± SEM | Plasma Avg. Scan Count ± SEM | Serum Avg. Scan Count ± SEM |
| Alpha-1 -antitrypsin | 2 ± 0.97 | 0.4 ± 0.52 | 39.8 ± 33.3 | 41 ± 43.8 |
| Alpha-2-macroglobulin | 475 ± 166 | 753 ± 171 | 11.1 ± 7.7 | 37.6 ± 38† |
| Serum Albumin | 5.8 ± 5 | 7 ± 5.4 | 324.5 ± 243.4 | 306.1 ± 221.1 |
| Alpha-1-microglobulin | 0 | 0.4 ± 0.9 | 2.3 ± 1.1 | 2.3 ± 1.1 |
| Apolipoprotein A-I | 9 ± 2.2 | 11 ± 2.3 | 123.1 ± 30 | 107.2 ± 42 |
| Apolipoprotein A-II | 2.5 ± 1 | 3.2 ± 1 | 24.2 ± 6.5 | 26.7 ± 11.1 |
| Apolipoprotein B-100 | 98 ± 19 | 167 ± 94† | 0.44 ± 0.42 | 0.56 ± 0.30 |
| Apolipoprotein C-III | 5.7 ± 3.4 | 11.2 ± 8.8 | 1.9 ± 0.61 | 1.7 ± 0.58 |
| Apolipoprotein E | 4.8 ± 2.5 | 7.4 ± 2.7 | 1.8 ± 0.81 | 1.2 ± 1 |
| Apolipoprotein-L1 | 2.3 ± 0.94 | 3 ± 1 | 0.78 ± 0.38 | 0.33 ± 0.29 |
| Complement C1 s subcomponent | 0.33 ± 0.3 | 0.8 ± 0.48 | 0.56 ± 0.3 | 0.78 ± 0.75 |
| C4b-binding protein | 17.5 ± 6.1 | 36 ± 28† | 0 | 0.33 ± 0.41 |
| Complement factor H | 3. 5 ± 2.9 | 6.8 ± 6.1 | 5.7 ± 5.4 | 6.6 ± 4.7 |
| Apolipoprotein J (Clusterin) | 2.3 ± 0.79 | 2.8 ± 2.1 | 2.6 ± 0.65 | 2.9 ± 1.3 |
| Complement C4-A | 1.7 ± 1 | 0.2 ± 0.25 | 38.8 ± 14.7 | 34.2 ± 16 |
| Coagulation factor XIII B chain | 0.67 ± 0.47 | 0 | 0 | 0.44 ± 0.42 |
| Fibrinogen alpha chain | 133.7 ± 35.3 * | 0 | 1.1 ± 1.1 | 0 |
| Fibrinogen beta chain | 149.2 ± 21 * | 0 | 2 ± 1.7 * | 0 |
| Fibrinogen gamma chain | 143 ± 28 * | 0 | 0.78 ± 0.9 | 0 |
| Fibronectin | 57.2 ± 24 | 98.8 ± 38† | 0.89 ± 0.79 | 0.44 ± 0.58 |
| Haptoglobin | 5.5 ± 4 | 19.2 ± 15.3† | 11.3 ± 9.3 | 7 ± 4.1 |
| Haptoglobin-related protein | 19 ± 14 | 47.6 ± 33† | 40.1 ± 28.8 | 29.4 ± 18 |
| Inter-alpha-trypsin inhibitor heavy chain H2 | 0.5 ± 0.48 | 1.8 ± 1.25 | 7.6 ± 4.4 | 10.3 ± 6.8 |
| Paraoxonase-1 | 0.5 ± 0.32 | 0.8 ± 1 | 2.7 ± 0.96 | 2.9 ± 1.1 |
| Prothrombin | 0 | 10.4 ± 2.1† | 6.6 ± 4 | 4 ± 2.8 |
| Vitronectin | 0.5 ± 0.3 | 1.8 ± 1.1 | 4.1 ± 2.6 | 3.4 ± 1.7 |
The average scan count ± SEM is provided for each protein identified in both the LDL and HDL fractions derived from plasma and serum. (P < 0.001; * significantly greater in plasma; †significantly greater in serum)