Table 1.
Summary of published studies retrospectively estimating measles case fatality ratios and conducted by the authors
| Reference | Location | Study type | Sampling | Recall Period | Study dates | Case Ascertainment |
Lab Confirmation | Case Fatality Ratio |
|---|---|---|---|---|---|---|---|---|
| 21 | Mirrah district, Niger | Retro-spective | 22 villages from 5 health districts selected based on number of cases and ability to lab confirm outbreak | Jan 1 - Apr 15 2003 | May 24 - June 28 2003 | House to house search; house-hold census in houses reporting cases; repeat visits to confirm deaths |
5-10 serum samples in 12 of 22 villages surveyed | 9.7% (95% CI: 7.9 - 11.5) |
| 24 | Boukoki, Niamey, Niger |
Retro-spective community-based |
One neighborhood selected based on population size and feasibility | Approx 6 months preceding survey | May 5 - 12, 2004 | House to house search, collection of demographic and measles case data in all households | At least 10 cases lab-confirmed per epidemic | 4.6% in children aged < 5 yrs |
| 22 | White Nile and Khartoum states, North Sudan | Retro-spective community-based |
One administrative unit in each of two states selected on basis of number of measles cases; within each administrative unit, 10 villages randomly selected | Oct 1 2003 - Apr 30 2004 | May 17 - July 8, 2004 | House to house search for measles cases; house-hold census in houses reporting cases |
Laboratory confirmation in each administrative unit | 0.9% (95% CI: 0.16 - 1.91) |
| 28 | Nepal -- nationwide | Retro-spective community-based |
Two stage random sampling for a total of one outbreak from each of 37 districts | March 1 - Sept 1 2004 | Sept 2004 - Jan 2005 | House to house search for measles cases; house-hold census in houses reporting cases |
Laboratory confirmation of outbreaks | 1.1% (95% CI: 0.5 - 2.3) |
| 24 | Moursal, Ndjamena, Chad | Retro-spective community-based |
One neighborhood selected based on population size and feasibility | Approx 6 months preceding survey | July 4 - 12, 2005 | House to house search, collection of demographic and measles case data in all household | At least 10 cases lab-confirmed per epidemic | 4.0% in children aged < 5 yrs |
| 24 | Dong District, Nigeria | Retro-spective community-based |
One neighborhood selected based on population size and feasibility | Approx 6 months preceding survey | Apr 25 - May 2, 2005 | House to house search, collection of demographic and measles case data in all household | At least 10 cases lab-confirmed per epidemic | 10.8% in children aged < 5 yrs |