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Abnormal development of astrocytes in Olig1cre/Dicer flox/flox mutant spinal cord. Transverse spinal cord sections at the thoracic level from E18.5 wild-type and mutant embryos were immunostained with anti-GFAP (A, B) and anti-S100β (C, D) antibodies, or subjected to ID3 in situ RNA hybridization. (E, F). The region devoid of GFAP or ID3 signal in the mutants is outlined by dashed lines.
