Table 2. Chemical structures of the compounds used in this study and their inhibition of HTLV-1 protease.
Proprietary name | Chemical structure | Percent inhibition (%) at 50 nM |
---|---|---|
Statine Inhibitor | 19 | |
KNI-10562 | 78 | |
KNI-10673 | 29 | |
KNI-10681 | 40 | |
KNI-10683 | 76 | |
KNI-10729 | 79 | |
KNI-10516 | 86 | |
KNI-1595b | 5 | |
KNI-10220 | 61 | |
KNI-10296c | 28 |