. Author manuscript; available in PMC: 2011 Aug 1.

Published in final edited form as: Depress Anxiety. 2010 Aug;27(8):737–745. doi: 10.1002/da.20715

Table 2.

Hierarchical Linear Regression Analysis of 5-HTTLPR, COMT val158met, Chronic Family Stress, and Their Interactions Predicting Depressive Symptoms at Age 20

	Step Statistics		Final Statistics
Predictors	ΔR²	b (SE b)	b (SE b)
Step 1	.18^**
Gender		−1.60 (0.90)^*	−1.49 (0.90)
Maternal Depression		2.49 (0.92)^**	2.66 (0.92)^**
Youth Prior Depression		2.06 (0.48)^**	2.06 (0.48)^**
Family Stress		3.88 (0.81)^**	−3.25 (2.51)
5-HTTLPR		−0.36 (0.97)	−0.60 (1.86)
COMT		1.25 (1.01)	1.14 (1.84)
Step 2	.01
Stress × 5-HTTLPR		2.57 (1.78)	10.01 (3.07)^**
Stress × COMT		0.47 (1.74)	8.12 (3.11)^**
5-HTTLPR × COMT		−0.32 (2.23)	−0.16 (2.20)
Step 3	.02^**
Stress × 5-HTTLPR × COMT			−11.04 (3.74)^**
Total R²	.21^**

p < .05

^**

p < .01