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. Author manuscript; available in PMC: 2011 Aug 15.
Published in final edited form as: Bioorg Med Chem. 2010 Jul 8;18(16):5925–5931. doi: 10.1016/j.bmc.2010.06.086

Table 1.

Summary of results for G4-(C-DOTA-Gd)28 (dota) and G4-(1B4M-DTPA-Gd)30 (dtpa)

Agent G4:chelate r1
(mM−1s−1)a 		r2
(mM−1s−1)a 		Half life
(min)b 		Rate of clearance
(min−1)c
dota 1:28 29.5 ± 1.5 61.6 ± 1.7 16.2 ± 1.2 0.063 ± 0.0046
dtpad 1:30 26.9 ± 1.2 56.1 ± 1.4 29.1 ± 0.63 0.034 ± 0.00017
a

Molar relaxivity values obtained from phantom measurements.

b

Blood clearance half-life as measured from R1 map of the jugular vein in dynamic MR angiographic images.

c

Blood clearance rates.

d

From reference.25 Reported numbers are the average values and errors are reported as standard deviations.